Innovation and Development

Better Solution for Cardiovascular Diseases

Recently, the Biomaterials and Devices Group headed by Prof. Yang Ke from the Institute of Metal Research, CAS chose AZ31 magnesium alloy as the material for biodegradable stent and independently designed and processed magnesium alloy coronary stents by laser cutting. Collaborated with the First Hospital of China Medical University, they successfully accomplished the experiment of in vivo implantation of the newly developed biodegradable magnesium alloy coronary stent. At the early stage of implantation, the magnesium alloy stent can support the pathological blood vessel and prevent the negative remodeling of pathological blood vessel. Along with the improvement of the environment around the pathological blood vessel and completion of structural remodeling of vessel, the magnesium alloy stent inside the blood vessel will corrode gradually until it is degraded completely at last, thus preventing the intimal hyperplasia and restenosis due to the irritation of stent to vessel wall at the later stage of implantation. The degradability of magnesium alloy stent not only produces good treatment effects on patients with common cardiovascular disease, but also has great therapeutic significance to infants and adolescents with congenital cardiovascular disease.

Nano-Al2O3 Reference Materials Developed for Specific Surface Area

On Nov. 16, 2009, the nano-Al2O3 reference material for specific surface area produced by the National Center for Nanoscience and Technology (NCNST) was approved as primary reference material for specific surface area by the State Bureau of Quality and Technical and Quarantine. The “State Certificate for the Gradation of Certified Reference Materials” and “License for Manufacturing Measuring Instruments” was awarded. The nano-Al2O3 reference material for specific surface area produced by NCNST is the first primary reference material for specific surface area in China with proprietary intellectual property right and international leading level and the first reference material for specific surface area developed from nanomaterials in China. The successful development of this reference material not only filled the gaps of reference material for high specific surface area at home and abroad, but also provided the traceability for the calibration of specific surface area analyzer and authoritative and uniform measurement data for the determination of specific surface area of nano-powder. Certified Reference Materials Number of the nano-Al2O3 reference material for specific surface area: GBW13901; certified value: 445.4 m2/g, uncertainty: 5.8 m2/g; License for Manufacturing Measuring Instruments Number: GZBW 10000973.